INHIBITORY ACTIVITY OF EXTRACTS OF THE BRAZILIAN CERRADO ON ANAEROBIC MICROORGANISMS AND ASSOCIATED WITH NOSOCOMIAL INFECTIONS

Abstract

The objective of this study was to evaluate the antimicrobial activity of extracts of plants from Brazilian savanna on oral microorganisms and opportunistic pathogens. For the test, it was prepared hydroalcoholic and aqueous extracts from 22 plant species used in the Northern, Northeastern and Midwestern Brazilians regions as part of folk medicine. These extracts were tested against Aggregatibacter actinomycetemcomitans ATCC 3384, Enterococcus faecalis ATCC 19433, Fusobacterium nucleatum ATCC 10953 e ATCC 25586, Porphyromonas gingivalis ATCC 33277, Prevotella intermedia ATCC 2564, Pseudomonas aeruginosa ATCC 10145 e Streptococcus mutans ATCC 35668. Initially it was performed a screening in order to determinate the antimicrobial activities of the extracts. In addition, it was conducted tests to evaluate the highest inhibitory dilution by mean of dilution broth method. The results evidenced that 20% of all tested extract presented antimicrobial activity on at least some targeted microorganisms, and the most active were the hydroalcoholic and aqueous extracts obtained from araçá and aroeira, which were active against all tested microorganisms. Key Words: Plants Medicinal, products with antimicrobial action, dental caries, periodontitis.